Cells | Free Full-Text | Microglial Progranulin: Involvement in Alzheimer's Disease and Neurodegenerative Diseases
Intracellular Proteolysis of Progranulin Generates Stable, Lysosomal Granulins that Are Haploinsufficient in Patients with Frontotemporal Dementia Caused by GRN Mutations | eNeuro
GRN-related Frontotemporal dementia (GRN-FTD)
Loss of TMEM106B and PGRN leads to severe lysosomal abnormalities and neurodegeneration in mice | EMBO reports
Progranulin as a therapeutic target in neurodegenerative diseases - ScienceDirect
Induced Pluripotent Stem Cell Models of Progranulin-Deficient Frontotemporal Dementia Uncover Specific Reversible Neuronal Defects - ScienceDirect
Characterization of lysosomal proteins Progranulin and Prosaposin and their interactions in Alzheimer's disease and aged brains: increased levels correlate with neuropathology | Acta Neuropathologica Communications | Full Text
Progranulin inhibits expression and release of chemokines CXCL9 and CXCL10 in a TNFR1 dependent manner | Scientific Reports
Cells | Free Full-Text | Microglial Progranulin: Involvement in Alzheimer's Disease and Neurodegenerative Diseases
![Progranulin [PGRN] - Marker of Neuroinflammation](https://adipogen.com/pub/media/wysiwyg/Landing-Pages/Progranulin/Roles_of_Progranulin.PNG "Progranulin [PGRN] - Marker of Neuroinflammation")
Progranulin [PGRN] - Marker of Neuroinflammation
SciELO - Brasil - Progranulin (PGRN) is serves as an inflammation-response biomarker and promotes lung damage in burn-induced Sepsis via the SIRT1 Pathways by ROS Progranulin (PGRN) is serves as an inflammation-response
Progranulin deficiency leads to reduced glucocerebrosidase activity | PLOS ONE
Frontiers | Progranulin Adsorbs to Polypropylene Tubes and Disrupts Functional Assays: Implications for Research, Biomarker Studies, and Therapeutics
Lysosomal functions of progranulin and implications for treatment of frontotemporal dementia: Trends in Cell Biology
Microorganisms | Free Full-Text | Association of Progranulin Gene Expression from Dyspeptic Patients with Virulent Helicobacter pylori Strains; In Vivo Model
Progranulin in frontotemporal lobar degeneration and neuroinflammation | Journal of Neuroinflammation | Full Text
PGRN mutations identified in FTLD patients. Schematic representation of... | Download Scientific Diagram
Progranulin as a therapeutic target in neurodegenerative diseases - ScienceDirect
Inactivation of CDK/pRb Pathway Normalizes Survival Pattern of Lymphoblasts Expressing the FTLD-Progranulin Mutation c.709-1G>A | PLOS ONE
Frontiers | Granulin in Frontotemporal Lobar Degeneration: Molecular Mechanisms of the Disease
A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses | Life Science Alliance
The FAM171A2 gene is a key regulator of progranulin expression and modifies the risk of multiple neurodegenerative diseases | Science Advances
Progranulin in neurodegenerative dementia - Wang - 2021 - Journal of Neurochemistry - Wiley Online Library
